By Klaus-Dieter Weltmann, Jörn Winter, Martin Polak, Jörg Ehlbeck, Thomas von Woedtke (auth.), Zdenko Machala, Karol Hensel, Yuri Akishev (eds.)
Non-thermal (cold) plasmas at atmospheric strain have lately stumbled on many leap forward functions in biology, medication, and nutrients safeguard. Plasmas can successfully kill micro organism, yeasts, moulds, spores, biofilms and different dangerous microorganisms, together with capability bio-terrorism brokers. they are often hired for bio-decontamination and sterilization of surfaces, clinical tools, water, air, foodstuff, even of residing tissues with no inflicting their harm. Direct or oblique plasma interplay with residing cells of microorganisms or maybe people permits novel bio-medical purposes, e.g. remedy of dermis ailments and ulcers. Plasma-enhanced blood coagulation coupled with its antiseptic homes proved luck in wound therapeutic and opens new chances in surgical procedure, emergency drugs and army functions. Plasma therapy permits telephone manipulations, their removing and exact move into the injured quarter, that could speed up wound therapeutic. Plasma brought on apoptosis (programmed telephone loss of life) of tumor cells brings forth a superb capability for melanoma therapy. in addition to, plasma permits painless therapy of dental caries, root canal disinfection, and different dentistry functions.
This publication is a range of reviewed manuscripts issuing from the NATO complicated learn Workshop Plasma for bio-decontamination, drugs and nutrients protection held in Jasná, Slovakia, on 15-18 March 2011. It presents a complete evaluate of the present wisdom and study actions targeted on the plasma purposes in components resembling bio-decontamination, water chemistry, results on cells; biofilm inactivation, UV sterilization, and drugs, in particular tissue remedy and wound therapeutic, in addition to dentistry and nutrition security.
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Additional info for Plasma for bio-decontamination, medicine and food security
The same bacterial samples were irradiated by biocidal UV C radiation (Hg lamp, 254 nm, 1 min) for comparison. Concentrations Δc(TBARs) correlated with the inactivation efficiencies of the discharges. UV C radiation induced almost no Dc(TBARS) despite its efficiency was very high. Obviously, UV dominant biocidal mechanism is not peroxidation of cell membranes. On the contrary, SC and TS plasma treatments significantly enhanced the TBARS concentration. This indicates that oxidations of cell membranes by reactive oxygen species ROS are important in microbial inactivation.
Machala et al. Fig. 10 Decontamination efficiency vs. energy (medians with first and third quartiles as error bars): dry or moist plastic foils 2 min treatment (left, 3 experimental sets with 4–6 samples each) and moist teeth 3 and 5 min treatment (right, 3 experimental sets with 5–7 samples each) efficient and less energetic. These preliminary findings are now being verified in the treatment of teeth contaminated by Streptococcus mutans biofilms. 4 Conclusions Bio-decontamination of water and surfaces contaminated by bacteria and spores (Salmonella typhimurium, Bacillus cereus) was tested in two DC discharges in atmospheric pressure air: streamer corona and transient spark.
Two atomic oxygen emission lines at 115 (1D−1D0) and 130 nm (3P−3S0) dominate the spectrum. Additionally, weak emission due to parts of the Schumann-Runge bands of O2 and a weak H line at 120 nm (2P−2S0) have been observed. We also expect that the emission spectrum contains the He*2 excimer continuum in the 58–100 nm range and a strong atomic oxygen line at 98 nm since these emission features have been observed by other authors in atmospheric pressure plasmas with helium . 7% of radiation between 115 and 875 nm is detectable on the axis of the side channel.
Plasma for bio-decontamination, medicine and food security by Klaus-Dieter Weltmann, Jörn Winter, Martin Polak, Jörg Ehlbeck, Thomas von Woedtke (auth.), Zdenko Machala, Karol Hensel, Yuri Akishev (eds.)