By Michael Bader

ISBN-10: 3527319204

ISBN-13: 9783527319206

ISBN-10: 3527626247

ISBN-13: 9783527626243

Edited through a popular scientist within the box with greater than two hundred excessive profile clinical courses to his identify, this can be the 1st booklet to supply a accomplished review of all cardiovascular hormone platforms. truly based, the textual content covers steroid and peptide hormones, amines, and arachidonic acid metabolites, to boot as nucleotides, nitric oxide, and acetylcholine. a vital reference for researchers engaged on the cardiovascular method and similar illnesses.

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Additional info for Cardiovascular Hormone Systems: From Molecular Mechanisms to Novel Therapeutics

Example text

2007) Aliskiren for renin inhibition: a new class of antihypertensives. Annals of Pharmacotherapy, 41, 456–64. A. J. (2006) Hypertension, kidney, and transgenics: a fresh perspective. Physiological Reviews, 86, 709–46. B. (1985) Analysis of longterm potassium regulation. Endocrine Reviews, 6, 24–44. W. E. (1976) Acute and chronic dose–response relationships for angiotensin, aldosterone, and arterial pressure at varying levels of sodium intake. Circulation Research, 39, 788–97. K. A. (2000) Pituitary–adrenal axis regulation in CRH-deficient mice.

Moreover, local vasodilation may be offset by blunting of the baroreceptor reflex [127] and indirect activation of the sympathetic nervous system. In addition to these well-documented responses, both mineralocorticoids and glucocorticoids will stimulate the local release of endothelin from the vasculature [128]. This is a potent vasoconstrictor (covered in Chapter 6) and could mediate aldosterone-stimulated increases in total peripheral resistance. Aldosterone also exerts profound pathological effects in the vasculature.

2006) Kidney function in mice lacking aldosterone. American Journal of Physiology – Renal Physiology, 290, F61–69. J. H. (1988) Regulation of aldosterone secretion. Annual Review of Physiology, 50, 409–26. C. (2007) The renin angiotensin system in the regulation of angiogenesis. Current Pharmaceutical Design, 13, 1215–29. , Gallant, S. C. (1980) Actions of angiotensin II on aldosterone biosynthesis in the rat adrenal cortex. Effects on cytochrome P-450 enzymes of the early and late pathway. Journal of Biological Chemistry, 255, 3442–7.

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Cardiovascular Hormone Systems: From Molecular Mechanisms to Novel Therapeutics by Michael Bader


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