By Kanu Chatterjee

ISBN-10: 935025879X

ISBN-13: 9789350258798

Cardiac medications describes the most recent advances within the quickly evolving quarter of cardiovascular pharmacology. Written by means of well known, USbased specialists in cardiology, this booklet discusses the drug teams for various ailments, reminiscent of acute coronary syndromes, high blood pressure, angina and middle failure. Separate chapters study cardiac medicines in being pregnant and lactation, and destiny instructions. more suitable by way of complete color photographs and illustrations, this simple to stick to textual content bargains useful suggestion on tips to deal with cardiac illnesses, with a spotlight on hands-on healing information for clinicians.

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Sample text

These results extend the benefit of aldosterone antagonists to patients with mild HF, a much broader population. It is widely expected that updated HF guidelines will incorporate the use of eplerenone for NYHA class II patients. 76 This is in part related to concerns regarding hyperkalemia. Spironolactone and Eplerenone: Are They the Same? Both spironolactone and eplerenone have been shown to reduce mortality in patients with systolic HF. However, a few differences exist. Due to its relatively greater specificity for the MR, eplerenone lacks the progestogenic and antiandrogenic off-target actions of spironolactone.

Bangalore S, Kumar S, Kjeldsen SE, Makani H, Grossman E, Wetterslev J, et al. Antihypertensive drugs and risk of cancer: network meta-analyses and trial sequential analyses of 324,168 participants from randomised trials. Lancet Oncol. 2011;12(1):65-82. 60. FDA drug safety communication: No increase in risk of cancer with certain blood pressure drugs—Angiotensin Receptor Blockers (ARBs). Jun 2, 2011. 61. Moltzer E, Essers J, van Esch JH, Roos-Hesselink JW, Danser AH. The role of the renin-angiotensin system in thoracic aortic aneurysms: clinical implications.

2009;302(15):1658-65. 77. Yamaji M, Tsutamoto T, Kawahara C, Nishiyama K, Yamamoto T, Fujii M, et al. Effect of eplerenone versus spironolactone on cortisol and hemoglobin A1(c) levels in patients with chronic heart failure. Am Heart J. 2010;160(5):915-21. 78. Sánchez-Más J, Turpín MC, Lax A, Ruipérez JA, Valdés Chávarri M, PascualFigal DA. Differential actions of eplerenone and spironolactone on the protective effect of testosterone against cardiomyocyte apoptosis in vitro. Rev Esp Cardiol. 2010;63(7):779-87.

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Cardiac Drugs by Kanu Chatterjee

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