By John R. Bradshaw (Auth.)
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Additional resources for Brain Imaging. An Introduction
Changes in the understanding and application of this technique are occurring almost daily. The descriptions 56 Brain imaging which follow are necessarily over-simplified and, furthermore, many of the concepts will inevitably be superseded as new research emerges. This is particularly likely in the case of pulse sequences and systems for data acquisition. Basic physical and biological principles Many atomic nuclei can be considered to act as spinning magnetic dipoles (Figure 97A). This model is an over-simplification, but will suffice for an understanding of the basic principles of NMR.
Broadly speaking the greater the proportion of free water present, the longer the Tl relaxation time will be. Conversely, when the proportion of bound water is highest then Tl will be shorter. This has an important practical application, as many different pathologies cause increased free water in the tissues and hence a prolonged Tl. The T2 relaxation time is dependent on nuclear spins going out of phase with those surrounding them. This parameter is particularly sensitive for the detection of disease processes.
This often affects their function and that of other adjacent structures. Figure 87 shows structures which are normally situated in the midline displaced to the left side (septum pellucidum). The right lateral ventricle is compressed and displaced to the left side of the midline. There is, therefore, a 'space-occupying' process in the right side of the head producing this mass effect. This lesion can be seen as a low density area outside the hemisphere due to a chronic subdural haematoma. Ventricular dilatation (hydrocephalus) is clearly demonstrated on CT.
Brain Imaging. An Introduction by John R. Bradshaw (Auth.)