By Leon V. Berhardt

ISBN-10: 1621000567

ISBN-13: 9781621000563

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Extra resources for Advances in Medicine and Biology, Volume 20

Example text

1996). To do this, several tests have been developed to determine the mutation frequency caused by mutagenic agents in somatic cells. Among them, the most frequently used are hypoxanthine-guanine phosphoribosyl-transferase (HPRT) and T cell receptor (TCR) mutation assays. In addition, cytogenetic tests have been traditionally employed for the evaluation of lead genotoxic effects. Among them, the most representative ones are sister chromatid exchanges (SCE), micronucleus (MN) test, and the study of DNA lesions such as structural and numeric chromosome aberrations (CA).

Polyethylene magnetic nanoparticle: a new magnetic material for biomedical applications. Journal of Magnetism and Magnetic Materials. 2002;246(3): 382-391. [27] Shi G, Rouabhia M, Wang Z, Dao LH, Zhang Z. A novel electrically conductive and biodegradable composite made of polypyrrole nanoparticles and polylactide. Biomaterials. 2004; 25(130:2477-2788. [28] Ye A, Flanagan I, Singh H. Formation of stable nanoparticle via electrostatic complexation between sodium caseinate and gum Arabic. Biopolymers.

With technical advancement in near future, a fully automated system for high-throughput separation, using protein chips with surfaceenhanced laser desorption, ionization mass spectrometry, is under development and could be an ext step in the analysis of cardiac troponins from biological samples. Conclusion Sandwich magnetic immunoassay is a commercial approach to detect separate out cardiac Troponin protein(s). However, present time, still it remains semi-quantitative while MALDITOF mass spectroscopy is further extension of protein subunit or peptide components precisely responsible for acute myocardial infarction process initially within 1-4 hours of disease progress.

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Advances in Medicine and Biology, Volume 20 by Leon V. Berhardt


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